Medicinal chemistry : an introduction /
Gareth Thomas.
- 2nd ed., Extensively rev. and updated.
- Chichester ; Hoboken, NJ : John Wiley, c2007.
- xxiv, 621 p. : ill. ; 25 cm.
Includes bibliographical references (p. [575]-577) and index.
An introduction to drugs, their action and discovery -- Drug structure and solubility -- Structure-activity and quantitative structures relationships -- Computer-aided drug design -- Combinatorial chemistry -- Drugs from natural sources -- Biological membranes -- Receptors and messengers -- Enzymes -- Nucleic acids -- Pharmacokinetics -- Drug metabolism -- Complexes and chelating agents -- Nitric oxide -- An introduction to drug and analogue synthesis -- Drug development and production.